(4) corticosteroids
for asthmatic bronchitis
(5) bronchial hygiene
¥². Chronic asthmatic bronchitis (chronic persistent asthma)
: chronic bronchitis¿¡¼ episodic airway obstructionÀ» ÀÏÀ¸Å² °æ¿ì
persistent airway obstruction
chronic productive cough
episodic bronchospasm
¥³. Chronic obstructive pulmonary disease
1. chronic bronchitis (chronic obstructive bronchitis)
2. emphysema
: diagnosed between ages 55 and 65
autopsy : 65% in adult men
15% in adult women
1) Pathogenesis
(1) smoking
smokerÀÇ 50% - cough with sputum, 10-15%´Â airway obstruction
¨ç protease
neutrophil elastase -> main
pulmonary alveolar macrophages -> possibly
¨è counteracted by ¥á1-antitrypsin (antiprotease), ¥á2-macroglobulin
(2) familial and genetic factors
alpha 1-antitrypsin deficiency (protease inhibitor)
(Pi system)
Genetic type¡¦(»ý·«)
¨ç hepatitis in infancy
¨è emphysema (panacinar) at lung base - 3rd, 4th, 5th decades
2) Pathology
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