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1. lac operon �씠��� 臾댁뾿�씤媛�?
Operon �씠��� Promoter, Operator, Structural Gene�벑�뿉 �쓽�븯�뿬 �넻�씪�쟻�쑝濡� 議곗젅�씠 �릺怨� �엳�뒗 �꽌濡� �씠�썐�븳 �쑀�쟾�옄援곗쓣 留먰븳�떎. lac operon��� 1960�뀈 Jacob, Perrin, Sanchez, Monod �뿉 �쓽�빐�꽌 洹� 媛쒕뀗�씠 �젣�븞�릺�뿀�쑝硫� �븯�굹�쓽 �쑀�쟾�옄 援곗씠 �뿬�윭 protein�쓣 coding�븯怨� �엳�쑝誘�濡�(polycistronic), �씠�쟾源뚯���쓽 one-gene, one-enzyme �씠濡좎쓣 諛섎컯�븳 寃껋씠�떎. lac operon�쓽 湲곕뒫��� lactose ����궗�뿉 愿�怨꾨맂 寃껋쑝濡�, E.coli媛� 諛곗���뿉�꽌 glucose媛� 怨좉컝�릺�뿀�쓣 寃쎌슦 �떎瑜� �뿉�꼫吏��썝�쑝濡� lactose瑜� �궗�슜�븯湲� �쐞�빐 諛쒗쁽�맂�떎. �뵲�씪�꽌 glucose媛� �뭾遺��븳 寃쎌슦�뿉�뒗 議곗젅�쑀�쟾�옄�뿉 �쓽�빐 �옉�룞�쓣 �븯吏� �븡�떎媛� glucose媛� 怨좉컝�릺�뿀�쓣 寃쎌슦 �옉�룞�븯湲� �떆�옉�븳�떎.
2. lac operon�쓽 援ъ꽦
�뿈 structural gene
1) 棺-galactosidase (lacZ): beta-galactosidase瑜� coding�븳�떎. lactose瑜� glucose��� galactose濡� 媛��닔遺꾪빐�븳�떎.
2) lactose permease (lacY): glactoside permease瑜� coding�븳�떎.�씠�뒗 �쇅遺��뿉 議댁옱�븯�뒗 lactose瑜� cell �븞�쑝濡� transport�븯�뒗 transmembrane protein�씠�떎
3) galactoside transacetylase (lacA): galactoside transacetylase瑜� coding�븳�떎.
�뿈 regulatory gene
1) lac repressor (lacI) : lactose媛� 議댁옱�븯吏� �븡�쓣 �븣 operator DNA site�뿉 寃고빀�븯�뿬 lac operon�쓽 transcript���(�깮�왂)
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�씤泥� 媛먯뿼 �젅�룷�듃 lac operon.hwp
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